Article
Pulmonary epithelial markers in phenotypes of chronic lung allograft dysfunction.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation - 1 Aug 2023
Levy Liran, Moshkelgosha Sajad, Huszti Ella, Hunter Sarah, Renaud-Picard Benjamin, Berra Gregory, Kawashima Mitsuaki, Fernandez-Castillo Juan, Fuchs Eyal, Dianti Milagros, Ghany Rasheed, Keshavjee Shaf, Singer Lianne G, Tikkanen Jussi, Martinu Tereza
Abstract excerpt
BACKGROUND: Airway epithelial injury is thought to be a key event in the pathogenesis of chronic lung allograft dysfunction (CLAD). We investigated whether markers of epithelial activity and injury in bronchoalveolar lavage fluid (BAL) correlate with CLAD diagnosis and major CLAD phenotypes: bronchiolitis obliterans syndrome (BOS) vs restrictive allograft syndrome (RAS)-related phenotypes (including RAS, mixed...
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