Article
Heterogeneity of chronic lung allograft dysfunction: insights from protein expression in broncho alveolar lavage.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation - 1 Jun 2011
Verleden Stijn E, Vos Robin, Mertens Veerle, Willems-Widyastuti Anna, De Vleeschauwer Stéphanie I, Dupont Lieven J, Verleden Geert M, Van Raemdonck Dirk E, Vanaudenaerde Bart M
Abstract excerpt
BACKGROUND: Chronic lung allograft dysfunction (CLAD) remains a major risk factor for death after lung transplantation. Previous data suggested that within CLAD at least 2 phenotypes are present: a neutrophilic type (nCLAD or neutrophilic reversible allograft dysfunction [NRAD]), reversible with azithromycin therapy, vs a low neutrophilic type, non-responsive to azithromycin (fibrotic bronchiolitis obliterans...
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