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Article

Rapamycin-Preactivated Autophagy Enhances Survival and Differentiation of Mesenchymal Stem Cells After Transplantation into Infarcted Myocardium.

Stem cell reviews and reports - 1 Apr 2020

Li Zhi-Hua, Wang Yong-Li, Wang Hai-Jie, Wu Jin-Hong, Tan Yu-Zhen

Abstract excerpt

Stem cell transplantation has been limited by poor survival of the engrafted cells in hostile microenvironment of the infarcted myocardium. This study investigated cytoprotective effect of rapamycin-preactivated autophagy on survival of the transplanted mesemchymal stem cells (MSCs). MSCs isolated from rat bone marrow were treated with 50 nmol/L rapamycin for 2 h, and then the cytoprotective effect of rapamycin...

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Identifiers

PMID: 31927699
DOI: 10.1007/s12015-020-09952-1
PMCID: PMC7152587

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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