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Article

By Targeting Atg7 MicroRNA-143 Mediates Oxidative Stress-Induced Autophagy of c-Kit+ Mouse Cardiac Progenitor Cells

30 May 2018

Abstract excerpt

Therapeutic efficiency of cardiac progenitor cells (CPCs) transplantation is limited by its low survival and retention in infarcted myocardium. Autophagy plays a critical role in regulating cell death and apoptosis, but the role of microRNAs (miRNAs) in oxidative stress-induced autophagy of CPCs remains unclear. This study aimed to explore if miRNAs mediate autophagy of c-kit + CPCs. We found that the silencing...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 29858017
DOI: 10.1016/j.ebiom.2018.05.021

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