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Article

Clinical Phenogroups in Heart Failure With Preserved Ejection Fraction: Detailed Phenotypes, Prognosis, and Response to Spironolactone.

JACC. Heart failure - 1 Mar 2020

Cohen Jordana B, Schrauben Sarah J, Zhao Lei, Basso Michael D, Cvijic Mary Ellen, Li Zhuyin, Yarde Melissa, Wang Zhaoqing, Bhattacharya Priyanka T, Chirinos Diana A, Prenner Stuart, Zamani Payman, Seiffert Dietmar A, Car Bruce D, Gordon David A, Margulies Kenneth, Cappola Thomas, Chirinos Julio A

Abstract excerpt

OBJECTIVES: This study sought to assess if clinical phenogroups differ in comprehensive biomarker profiles, cardiac and arterial structure/function, and responses to spironolactone therapy. BACKGROUND: Previous studies identified distinct subgroups (phenogroups) of patients with heart failure with preserved ejection fraction (HFpEF). METHODS: Among TOPCAT (Treatment of Preserved Cardiac Function Heart Failure...

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Identifiers

PMID: 31926856
DOI: 10.1016/j.jchf.2019.09.009
PMCID: PMC7058514

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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