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Phenotypes of heart failure with preserved ejection fraction and effect of spironolactone treatment.

ESC heart failure - 1 Aug 2022

Choy Manting, Liang Weihao, He Jiangui, Fu Michael, Dong Yugang, He Xin, Liu Chen

Abstract excerpt

AIMS: The aims of this study were to explore phenotypes of heart failure with preserved ejection fraction (HFpEF) and evaluate differential effects of spironolactone treatment. METHODS AND RESULTS: A swap-stepwise algorithm was used for variable selection. Latent class analysis based on 10 selected variables was employed in a derivative set of 1540 patients from the TOPCAT trial. Cox proportional hazard models...

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Heart Failure
Hospitalization
Phenotype
Stroke Volume

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 35587714
DOI: 10.1002/ehf2.13969
PMCID: PMC9288804

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