Article
Genetic Polymorphism and Serum Levels of RORc2 in Rheumatoid Arthritis.
The Egyptian journal of immunology - 1 Jul 2019
Abdelsamea Fatma S, Mohamed Mona S, Afifi Noha A, Hassanein Khaled M, Elzohri Mona H
Abstract excerpt
RORc2 is the master transcription factor of T helper 17 cells. We aimed to evaluate whether RORc2 genetic polymorphism and serum levels have association with the risk and activity of rheumatoid arthritis (RA). RORC genetic polymorphisms were investigated by real time PCR. Serum RORc2 protein levels were determined by enzyme-linked immunosorbent assay. Protective effects of rs370515 CT, rs370515 CT + TT, rs3828057...
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