Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Treating sickle cell anemia: A new era dawns

11 Jan 2020

Abstract excerpt

A single mutation in the β-hemoglobin gene allows deoxyHbS to polymerize and initiate the complex pathophysiology of sickle cell disease, a hemolytic anemia with chronic complications punctuated by acute events (Figure 1).1, 2 This commentary encompasses certain assumptions: opinions on how to use new therapeutics are many-data are limited; drugs preventing HbS polymerization are the most efficacious and should...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Hemoglobinopathies and Related Disorders
Share to Iron Metabolism and Disorders
Share to Prenatal Screening and Diagnostics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 31925819
DOI: 10.1002/ajh.25724

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Treating sickle cell anemia: A new era dawnsPMID 31925819Read ↗

Hydroxyurea Treatment for Sickle Cell DiseaseSemantic proximity Read ↗

Sickle Cell Anemia and Antisickling Agents Then and NowSemantic proximity Read ↗

Research in Sickle Cell Disease: From Bedside to Bench to BedsideSemantic proximity Read ↗

Hydroxyurea in the sickle cell disease modern eraSemantic proximity Read ↗

Current and emerging treatments for sickle cell diseaseSemantic proximity Read ↗

Sickle cell anemia, the first molecular disease: overview of molecular etiology, pathophysiology, and therapeutic approaches.Semantic proximity Read ↗

Recent Advances in the Treatment of Sickle Cell DiseaseSemantic proximity Read ↗

Chronic Administration of Hydroxyurea (HU) Benefits Caucasian Patients with Sickle-Beta Thalassemia.Semantic proximity Read ↗

Sickle Cell Disease: Genetics, Cellular and Molecular Mechanisms, and TherapiesSemantic proximity Read ↗

Sickle Cell Disease.Semantic proximity Read ↗

Sickle Cell DiseaseSemantic proximity Read ↗

Optimizing hydroxyurea therapy for sickle cell anemia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.