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Article

Rapid comparative genomic analysis for clinical microbiology: the Francisella tularensis paradigm.

Genome research - 1 May 2008

La Scola Bernard, Elkarkouri Khalid, Li Wenjun, Wahab Tara, Fournous Ghislain, Rolain Jean-Marc, Biswas Silpak, Drancourt Michel, Robert Catherine, Audic Stéphane, Löfdahl Sven, Raoult Didier

Abstract excerpt

It is critical to avoid delays in detecting strain manipulations, such as the addition/deletion of a gene or modification of genes for increased virulence or antibiotic resistance, using genome analysis during an epidemic outbreak or a bioterrorist attack. Our objective was to evaluate the efficiency of genome analysis in such an emergency context by using contigs produced by pyrosequencing without time-consuming...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 18407970
DOI: 10.1101/gr.071266.107
PMCID: PMC2336804

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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