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Article

Transmembrane 6 superfamily member 2 167K allele improves renal function in children with obesity.

Pediatric research - 1 Aug 2020

Marzuillo Pierluigi, Di Sessa Anna, Cirillo Grazia, Umano Giuseppina Rosaria, Pedullà Marcella, La Manna Angela, Guarino Stefano, Miraglia Del Giudice Emanuele

Abstract excerpt

BACKGROUND: The transmembrane 6 superfamily member 2 (TM6SF2) E167K polymorphism influences estimated glomerular filtration rate (eGFR) in adults without diabetes and without obesity. We aimed exploring the impact of this polymorphism on eGFR in children with obesity with and without non-alcoholic fatty liver disease (NAFLD). METHODS: We genotyped 531 children with obesity for TM6SF2 E167K polymorphism. NAFLD was...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 31923913
DOI: 10.1038/s41390-020-0753-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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