Article
Associations of TM6SF2 167K allele with liver enzymes and lipid profile in children: the PANIC Study.
Pediatric research - 1 May 2016
Viitasalo Anna, Pihlajamäki Jussi, Paananen Jussi, Atalay Mustafa, Lindi Virpi, Lakka Timo A
Abstract excerpt
BACKGROUND: The 167K allele in the TM6SF2 gene has been suggested to protect against cardiovascular disease at the cost of developing nonalcoholic fatty liver disease in adults. METHODS: We performed a cross-sectional study in a population sample of 462 Caucasian children aged 6-9 y, genotyped the polymorphism using HumanCoreExome BeadChip, and assessed several cardiometabolic risk factors. RESULTS: The 51 (11%)...
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