Article
Pediatric non-alcoholic fatty liver disease and kidney function: Effect of HSD17B13 variant.
World journal of gastroenterology - 28 Sept 2020
Di Sessa Anna, Umano Giuseppina Rosaria, Cirillo Grazia, Passaro Antonio Paride, Verde Valentina, Cozzolino Domenico, Guarino Stefano, Marzuillo Pierluigi, Miraglia Del Giudice Emanuele
Abstract excerpt
BACKGROUND: Growing evidence supports a genetic link between non-alcoholic fatty liver disease (NAFLD) and chronic kidney disease (CKD). Interesting data demonstrated that both the major NAFLD risk polymorphisms such as the I148M polymorphism in the patatin like phospholipase containing domain 3 (PNPLA3) and the E167K allele in the transmembrane 6 superfamily member 2 gene (TM6SF2) affect renal function. Recently...
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