Article
Familial cancer syndromes: catalog with comments.
Cytogenetic and genome research - 1 Jan 2007
Hecht F
Abstract excerpt
A catalog of 50 family cancer syndromes is presented, representing all Mendelian modes of inheritance and influential genes on chromosomes 1-20, 22 and the X. Certain trends are emerging such as recurrent involvement of the RecQ family of DNA helicases and somatic overgrowth in the family cancer syndromes. A big question now is: can family cancer syndromes be reliably spotted by primary care clinicians?
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