Article
Tubulointerstitial damage and interstitial immune cell phenotypes are useful predictors for renal survival and relapse in antineutrophil cytoplasmic antibody-associated vasculitis.
Journal of nephrology - 1 Aug 2020
Bitton Laura, Vandenbussche Cyrille, Wayolle Nicolas, Gibier Jean-Baptiste, Cordonnier Carole, Verine Jérôme, Humez Sarah, Bataille Pierre, Lenain Rémi, Ramdane Nassima, Azar Raymond, Mac Namara Evelyne, Hatron Pierre-Yves, Maurage Claude-Alain, Perrais Michael, Frimat Marie, Vanhille Philippe, Glowacki François, Buob David, Copin Marie-Christine, Quéméneur Thomas, Gnemmi Viviane
Abstract excerpt
The aims of this study were to determine whether tubulointerstitial damage in the form of interstitial fibrosis/tubular atrophy and total interstitial inflammation predicted progression to end stage renal disease (ESRD) and/or renal relapse (RR) in patients with antineutrophil cytoplasmic antibody-associated vasculitis (AAV). One hundred thirteen patients with AAV from six French centers with an index biopsy...
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