Article
Analysis and Validation of Antineutrophil cytoplasmic antibody-associated vasculitis with renal injury of the ferroptosis-related gene CD44 and Pan-Cancer
2022-12-14
Abstract excerpt
<h4>Objective: </h4> To investigate the role of ferroptosis in Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) with renal injury. <h4>Methods: </h4> GSE104954 and GSE108112 were retrieved from the GEO database and concatenated into one dataset. Expression of ferroptosis-related genes (FRGs) was extracted for differential analysis. The ferroptosis signature genes were identified by LASSO reg...
Topics
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- Adipokines, Inflammation, and Metabolic Diseases
- Cancer-related gene regulation
- Cancer-related molecular mechanisms research
- Ferroptosis and cancer prognosis
- Genetic factors in colorectal cancer
- Inflammasome and immune disorders
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- RNA modifications and cancer
Identifiers and source
- Literature Corpus work
- e1146f85-57c8-5922-96a2-e3a15cc30ada
- DOI
- 10.21203/rs.3.rs-2342623/v1
