Article
BRCA1/2 mutation status in patients with metachronous breast and ovarian malignancies: clues towards the implementation of genetic counseling.
Journal of gynecologic oncology - 1 May 2020
Chao Angel, Lin Yi Hao, Yang Lan Yan, Wu Ren Chin, Chang Wei Yang, Chang Pi Yueh, Chang Shih Cheng, Lin Chiao Yun, Huang Huei Jean, Lin Cheng Tao, Chou Hung Hsueh, Huang Kuan Gen, Kuo Wen Ling, Chang Ting Chang, Lai Chyong Huey
Abstract excerpt
OBJECTIVE: The characteristics of patients with metachronous breast and ovarian malignancies and the pathogenic role of BRCA1/2 mutations remain poorly understood. We investigated these issues through a review of hospital records and nationwide Taiwanese registry data, followed by BRCA1/2 mutation analysis in hospital-based cases. METHODS: We retrospectively retrieved consecutive clinical records of Taiwanese...
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