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Germline breast cancer susceptibility gene mutations and breast cancer outcomes.

BMC cancer - 22 Mar 2018

Wang Yong Alison, Jian Jhih-Wei, Hung Chen-Fang, Peng Hung-Pin, Yang Chi-Fan, Cheng Hung-Chun Skye, Yang An-Suei

Abstract excerpt

BACKGROUND: It is unclear whether germline breast cancer susceptibility gene mutations affect breast cancer related outcomes. We wanted to evaluate mutation patterns in 20 breast cancer susceptibility genes and correlate the mutations with clinical characteristics to determine the effects of these germline mutations on breast cancer prognosis. METHODS: The study cohort included 480 ethnic Chinese individuals in...

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Identifiers

PMID: 29566657
DOI: 10.1186/s12885-018-4229-5
PMCID: PMC5863855

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BRCA2

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