Article
Mumps virus diagnosis and genotyping using a novel single RT-PCR.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Dec 2011
Royuela Enrique, Castellanos Ana, Sánchez-Herrero Carmen, Sanz Juan Carlos, De Ory Fernando, Echevarria J E
Abstract excerpt
BACKGROUND: IgM detection is considered as the gold standard for mumps diagnosis. Currently, most cases in developed countries occur in highly vaccinated populations due to secondary vaccine failure. In these patients, pre-existing vaccine-induced antibodies are not able to neutralise the virus, but prevent the typical primary response, so that specific IgM is not always elicited. Consequently, acute infection...
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