Article
A Mendelian randomization study on the effect of 25-hydroxyvitamin D levels on periodontitis.
Journal of periodontology - 1 Aug 2022
Baumeister Sebastian-Edgar, Reckelkamm Stefan Lars, Baurecht Hansjörg, Nolde Michael, Kocher Thomas, Holtfreter Birte, Ehmke Benjamin, Hannemann Anke
Abstract excerpt
BACKGROUND: Twenty five-hydroxy vitamin D (25OHD) levels have been proposed to protect against periodontitis based on in vitro and observational studies but evidence from long-term randomized controlled trials (RCTs) is lacking. This study tested whether genetically proxied 25OHD is associated with periodontitis using Mendelian randomization (MR). METHODS: Genetic variants strongly associated with 25OHD in a...
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