Article
Cocaine-associated atypical haemolytic uraemic syndrome in a genetically susceptible individual.
Nephrology (Carlton, Vic.) - 1 Jul 2020
Bongetti Elisa, Kavanagh David, Martin Kylie, Bendall Anna, Hill Prue, Steinberg Adam, Rajaram Yogeshwar, Ierino Francesco
Abstract excerpt
Atypical haemolytic uraemic syndrome (aHUS) is a severe, life-threatening condition that requires early recognition and urgent treatment. In aHUS rare genetic variants in CFH, CFI, CD46, C3 and CFB predispose to complement over activation. This case describes a case of aHUS in which there was a strong temporal association between disease onset and the use of smoked cocaine. The patient was found to have a rare...
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