Article
Study of KIR gene expression at the mRNA level in specific donor-derived NK cells after allogeneic HSCT.
Immunogenetics - 1 Apr 2020
Li Ying, Wang Tian, Hu Xing, Zhang Huanhuan, Chen Luyao, Bao Xiaojing, He Jun
Abstract excerpt
The function of natural killer (NK) cells after allogeneic hematopoietic stem cell transplantation (allo-HSCT) is regulated by the balance between inhibitory KIRs (iKIRs) and activating KIRs (aKIRs). However, few studies have examined the subsequent expression of KIR genes unique to the donor. We defined the set of KIR genes expressed only in the donor and designed a method for measuring the expression of these...
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