Article
Analysis of KIR genes in HLA-identical sibling hematopoietic stem cell transplantation in Thai patients with leukemia.
Journal of the Medical Association of Thailand = Chotmaihet thangphaet - 1 Oct 2012
Wongwuttisaroj Natta, Vejbaesya Sasijit, Chongkolwatana Viroje, Issaragrisil Surapol
Abstract excerpt
BACKGROUND: Killer cell immunoglobulin-like receptors (KIRs) are members of a group of regulatory molecules found on the natural killer (NK) cells that regulate NK cells function by interacting with the human leukocyte antigen (HLA) class I molecules or ligands. The effects of KIR genes on the outcome of hematopoietic stem cell transplantation (HSCT) are still controversial. OBJECTIVE: To investigate the...
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