Article
Evolving phenotypes to endotypes: is precision medicine achievable in asthma?
Expert review of respiratory medicine - 1 Feb 2020
Bagnasco Diego, Passalacqua Giovanni, Caminati Marco, Heffler Enrico, Menzella Francesco, De Ferrari Laura, Riccio Anna Maria, Folli Chiara, Canonica Giorgio Walter
Abstract excerpt
Introduction: The development of biologic molecules led to a drastic change in the therapeutic approach to asthma. With the prospect of acting on different pathophysiological mechanisms of the disease, the idea of precision medicine was developed, in which a single molecule is able to modify a specific triggering mechanism. Thus, it seemed limiting to stop at the distinction of patients phenotypes and the concept...
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