Article
Phenotypes/endotypes-driven treatment in asthma.
Current opinion in allergy and clinical immunology - 1 Jun 2018
Braido Fulvio, Tiotiu Angelica, Kowal Krzysztof, Mihaicuta Stefan, Novakova Plamena, Oguzulgen Ipek Kivilcim
Abstract excerpt
PURPOSE OF REVIEW: Target therapy is the necessary step towards personalized medicine. The definition of asthma phenotypes and underlying mechanisms (endotypes) represent a key point in the development of new asthma treatments. Big data analysis, biomarker research and the availability of monoclonal antibodies, targeting specific cytokines is leading to the rapid evolution of knowledge. In this review, we sought...
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