Article
Integrative genomics reveal a role for MCPIP1 in adipogenesis and adipocyte metabolism.
Cellular and molecular life sciences : CMLS - 1 Dec 2020
Losko Magdalena, Dolicka Dobrochna, Pydyn Natalia, Jankowska Urszula, Kedracka-Krok Sylwia, Kulecka Maria, Paziewska Agnieszka, Mikula Michal, Major Piotr, Winiarski Marek, Budzynski Andrzej, Jura Jolanta
Abstract excerpt
Obesity is considered a serious chronic disease, associated with an increased risk of developing cardiovascular diseases, non-alcoholic fatty liver disease and type 2 diabetes. Monocyte chemoattractant protein-1-induced protein-1 (MCPIP1) is an RNase decreasing stability of transcripts coding for inflammation-related proteins. In addition, MCPIP1 plays an important role in the regulation of adipogenesis in vitro...
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