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Article

Intravenous leiomyomatosis: molecular analysis of 17 cases.

Pathology - 1 Feb 2020

Lu Bingjian, Liu Qin, Tang Lanlan, Ma Yu, Shi Haiyan

Abstract excerpt

Intravenous leiomyomatosis (IVL) is a rare smooth muscle tumour with a benign histology but with a quasi-malignant intravascular growth. In this study, we investigated the molecular alterations in 17 IVL cases composed of concurrent uterine leiomyoma (n=12), uterine IVL (n=17) and extra-uterine IVL (n=12). We found that eight tumours had a somatic MED12 mutation (c.130G>A, p.G44S, n=7; c.131G>C, p.G44A, n=1). The...

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Identifiers

PMID: 31889549
DOI: 10.1016/j.pathol.2019.10.009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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