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Integrated genome analysis of uterine leiomyosarcoma to identify novel driver genes and targetable pathways

24 Oct 2017

Abstract excerpt

Uterine leiomyosarcomas (uLMS) are rare, aggressive malignancies for which limited treatment options are available. To gain novel molecular insights into uLMS and identify potential novel therapeutic targets, we characterized 84 uLMS samples for genome-wide somatic copy number alterations, mutations, gene fusions and gene expression and performed a data integration analysis. We found that alterations affecting...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 29063609
DOI: 10.1002/ijc.31129

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