Article
Adverse Events of Concurrent Radiotherapy and ALK Inhibitors for Brain Metastases of ALK-Rearranged Lung Adenocarcinoma.
In vivo (Athens, Greece) - 1 Jan 2000
Nakashima Takaaki, Nonoshita Takeshi, Hirata Hidenari, Inoue Kouji, Nagashima Akira, Yoshitake Tadamasa, Asai Kaori, Shioyama Yoshiyuki
Abstract excerpt
BACKGROUND: We investigated acute adverse events in patients with brain metastases (BMs) of anaplastic lymphoma kinase-rearranged (ALKr) non-small cell lung cancer (NSCLC) treated with both cranial radiotherapy and tyrosine kinase inhibitors (TKIs) of ALK. PATIENTS AND METHODS: Acute AEs were retrospectively investigated in patients with BMs of ALKr-NSCLC who received both whole-brain radiotherapy (WBRT) and...
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