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Article

Brain metastases from non-small cell lung cancer with EGFR or ALK mutations: A systematic review and meta-analysis of multidisciplinary approaches.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology - 1 Mar 2020

Singh Raj, Lehrer Eric J, Ko Stephen, Peterson Jennifer, Lou Yanyan, Porter Alyx B, Kotecha Rupesh, Brown Paul D, Zaorsky Nicholas G, Trifiletti Daniel M

Abstract excerpt

BACKGROUND AND PURPOSE: To analyze outcomes of non-small cell lung cancer (NSCLC) patients with brain metastases harboring EGFR or ALK mutations and examine for differences between tyrosine kinase inhibitors (TKIs) alone, radiotherapy (RT) alone (either whole brain radiation therapy (WBRT) or stereotactic radiosurgery (SRS)), or combined TKIs and RT. MATERIALS AND METHODS: Thirty studies were identified....

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Identifiers

PMID: 31812932
DOI: 10.1016/j.radonc.2019.11.010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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