Article
Impact of EGFR mutation and ALK rearrangement on the outcomes of non-small cell lung cancer patients with brain metastasis.
Neuro-oncology - 20 Feb 2020
Balasubramanian Suresh K, Sharma Mayur, Venur Vyshak A, Schmitt Philipp, Kotecha Rupesh, Chao Samuel T, Suh John H, Angelov Lilyana, Mohammadi Alireza M, Vogelbaum Michael A, Barnett Gene H, Jia Xuefei, Pennell Nathan A, Ahluwalia Manmeet S
Abstract excerpt
BACKGROUND: The impact of activating alterations in non-small cell lung cancer (NSCLC) (epidermal growth factor receptor [EGFR] mutation/anaplastic lymphoma kinase [ALK] translocation) in prognosticating patients with brain metastasis (BM) is not well defined. This study was sought to identify this impact in NSCLC patients with BM accounting for the known validated variables. METHODS: Among 1078 NSCLC-BM patients...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.