Association of autophagy status with amount of Fusobacterium nucleatum in colorectal cancer.

doi:10.1002/path.5381

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Article

Association of autophagy status with amount of Fusobacterium nucleatum in colorectal cancer.

The Journal of pathology - 1 Apr 2020

Haruki Koichiro, Kosumi Keisuke, Hamada Tsuyoshi, Twombly Tyler S, Väyrynen Juha P, Kim Sun A, Masugi Yohei, Qian Zhi Rong, Mima Kosuke, Baba Yoshifumi, da Silva Annacarolina, Borowsky Jennifer, Arima Kota, Fujiyoshi Kenji, Lau Mai Chan, Li Peilong, Guo Chunguang, Chen Yang, Song Mingyang, Nowak Jonathan A, Nishihara Reiko, Yanaga Katsuhiko, Zhang Xuehong, Wu Kana, Bullman Susan, Garrett Wendy S, Huttenhower Curtis, Meyerhardt Jeffrey A, Giannakis Marios, Chan Andrew T, Fuchs Charles S, Ogino Shuji

Abstract excerpt

Fusobacterium nucleatum (F. nucleatum), which has been associated with colorectal carcinogenesis, can impair anti-tumour immunity, and actively invade colon epithelial cells. Considering the critical role of autophagy in host defence against microorganisms, we hypothesised that autophagic activity of tumour cells might influence the amount of F. nucleatum in colorectal cancer tissue. Using 724 rectal and colon...

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Identifiers

PMID: 31880318
DOI: 10.1002/path.5381
PMCID: PMC7282529

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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