Article
Advancing stroke therapeutics through genetic understanding.
Current drug targets - 1 Jul 2007
Ross O A, Worrall B B, Meschia J F
Abstract excerpt
Stroke is a complex neurological disorder that most likely results from an intricate interplay between lifestyle, environment and genetics. Genes can influence susceptibility to stroke, alter responses to pharmacotherapy, and affect disease outcome. Recently, common variations within the PDE4D and ALOX5AP genes have been identified that increase population-attributable risk of stroke in Iceland. These genes are...
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