Article
Concomitant genomic alterations in KRAS mutant advanced lung adenocarcinoma.
Lung cancer (Amsterdam, Netherlands) - 1 Feb 2020
Gibert Joan, Clavé Sergi, Hardy-Werbin Max, Taus Álvaro, Rocha Pedro, Longarón Raquel, Piquer Gabriel, Chaib Imane, Carcereny Enric, Morán Teresa, Salido Marta, Dalmases Alba, Bellosillo Beatriz, Arriola Edurne
Abstract excerpt
OBJECTIVES: KRAS mutations are one of the most prevalent alterations in non-small cell lung cancer. However, patients with this driver alteration present heterogeneous clinical outcomes. In this study, we have explored the potential clinical impact of coexisting alterations in this subset of patients. MATERIALS AND METHODS: Samples from a cohort of 69 lung adenocarcinoma patients homogenously treated with...
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