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Article

Splicing Dysregulation as Oncogenic Driver and Passenger Factor in Brain Tumors.

Cells - 18 Dec 2019

Bielli Pamela, Pagliarini Vittoria, Pieraccioli Marco, Caggiano Cinzia, Sette Claudio

Abstract excerpt

Brain tumors are a heterogeneous group of neoplasms ranging from almost benign to highly aggressive phenotypes. The malignancy of these tumors mostly relies on gene expression reprogramming, which is frequently accompanied by the aberrant regulation of RNA processing mechanisms. In brain tumors, defects in alternative splicing result either from the dysregulation of expression and activity of splicing factors, or...

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Identifiers

PMID: 31861467
DOI: 10.3390/cells9010010
PMCID: PMC7016899

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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