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Article

TP53BP2: Roles in suppressing tumorigenesis and therapeutic opportunities

5 Sept 2022

Abstract excerpt

Malignant tumor is still a major problem worldwide. During tumorigenesis or tumor development, tumor suppressor p53-binding protein 2 (TP53BP2), also known as apoptosis stimulating protein 2 of p53 (ASPP2), plays a critical role in p53 dependent and independent manner. Expression of TP53BP2 is highly correlated with the prognosis and survival rate of malignant tumor patients. TP53BP2 can interact with p53, NF-κB...

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Identifiers

PMID: 37492707
DOI: 10.1016/j.gendis.2022.08.014

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