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Article

Pseudomonas aeruginosa mexT is an indicator of PAO1 strain integrity.

Journal of medical microbiology - 1 Jan 2020

LoVullo Eric D, Schweizer Herbert P

Abstract excerpt

Laboratory research with Pseudomonas aeruginosa commonly involves the prototype strain PAO1. There is continued concern that PAO1 sublines maintained and propagated in the same laboratory or different laboratories exhibit genetic and phenotypic variability that may affect the reproducibility and validity of research. Whole-genome sequencing and other research identified the mexT locus as a mutational hotspot, but...

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PMID: 31859619
DOI: 10.1099/jmm.0.001128
PMCID: PMC7363278

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