Article
Whole-genome sequence variation among multiple isolates of Pseudomonas aeruginosa.
Journal of bacteriology - 1 Feb 2003
Spencer David H, Kas Arnold, Smith Eric E, Raymond Christopher K, Sims Elizabeth H, Hastings Michele, Burns Jane L, Kaul Rajinder, Olson Maynard V
Abstract excerpt
Whole-genome shotgun sequencing was used to study the sequence variation of three Pseudomonas aeruginosa isolates, two from clonal infections of cystic fibrosis patients and one from an aquatic environment, relative to the genomic sequence of reference strain PAO1. The majority of the PAO1 genome is represented in these strains; however, at least three prominent islands of PAO1-specific sequence are apparent....
Topics
- Adolescent
- Bacterial Proteins
- Child, Preschool
- Cystic Fibrosis
- Genetic Variation
- Genome, Bacterial
- Humans
- Molecular Sequence Data
- O Antigens
- Oligopeptides
- Pigments, Biological
- Pseudomonas Infections
- Pseudomonas aeruginosa
