Article
Intraclonal genome diversity of the major Pseudomonas aeruginosa clones C and PA14.
Environmental microbiology reports - 1 Apr 2016
Fischer Sebastian, Klockgether Jens, Morán Losada Patricia, Chouvarine Philippe, Cramer Nina, Davenport Colin F, Dethlefsen Sarah, Dorda Marie, Goesmann Alexander, Hilker Rolf, Mielke Samira, Schönfelder Torben, Suerbaum Sebastian, Türk Oliver, Woltemate Sabrina, Wiehlmann Lutz, Tümmler Burkhard
Abstract excerpt
Bacterial populations differentiate at the subspecies level into clonal complexes. Intraclonal genome diversity was studied in 100 isolates of the two dominant Pseudomonas aeruginosa clones C and PA14 collected from the inanimate environment, acute and chronic infections. The core genome was highly conserved among clone members with a median pairwise within-clone single nucleotide sequence diversity of 8 × 10(-6)...
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