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Caspase-3 knockout inhibits intervertebral disc degeneration related to injury but accelerates degeneration related to aging

18 Dec 2019

Abstract excerpt

Approximately 40% of people under 30 and over 90% of people 55 or older suffer from moderate-to-severe levels of degenerative intervertebral disc (IVD) disease in their lumbar spines. Surgical treatments are sometimes effective; however, the treatment of back pain related to IVD degeneration is still a challenge; therefore, new treatments are necessary. Apoptosis may be important in IVD degeneration because...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 31852919
DOI: 10.1038/s41598-019-55709-3

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