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Molecular subtypes based on DNA methylation predict prognosis in colon adenocarcinoma patients

18 Dec 2019

Abstract excerpt

Tumor heterogeneity makes early diagnosis and effective treatment of colon adenocarcinoma difficult. As an important regulator of gene expression, DNA methylation can influence tumor heterogeneity. In this study, we explored the prognostic value of subtypes based on DNA methylation status in 424 colon adenocarcinoma samples from the Cancer Genome Atlas database. Differences in DNA methylation levels were...

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PMID: 31852837
DOI: 10.18632/aging.102492

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