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Article

FOXO1 regulates developmental lymphangiogenesis by upregulating CXCR4 in the mouse-tail dermis

18 Dec 2019

Abstract excerpt

ABSTRACT Lymphangiogenesis plays important roles in normal fetal development and postnatal growth. However, its molecular regulation remains unclear. Here, we have examined the function of forkhead box protein O1 (FOXO1) transcription factor, a known angiogenic factor, in developmental dermal lymphangiogenesis using endothelial cell-specific FOXO1-deficient mice. FOXO1-deficient mice showed disconnected and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 31852686
DOI: 10.1242/dev.181545

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