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Article

Coordinated lymphangiogenesis is critical in lymph node development and maturation

13 Sept 2016

Abstract excerpt

Background: Lymph node (LN) formation requires multiple but coordinated signaling from intrinsic and extrinsic cellular components during embryogenesis. However, the contribution and role of lymphatic vessels (LVs) in LN formation and maturation are poorly defined. Here, using lymphatic‐specific reporters, Prox1‐GFP mice and Vegfc+/LacZ mice, we analyzed migration, assembly, and ingrowth of lymphatic endothelial...

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PMID: 27623309
DOI: 10.1002/dvdy.24456

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