ForestQC: Quality control on genetic variants from next-generation sequencing data using random forest.

Abstract excerpt

Next-generation sequencing technology (NGS) enables the discovery of nearly all genetic variants present in a genome. A subset of these variants, however, may have poor sequencing quality due to limitations in NGS or variant callers. In genetic studies that analyze a large number of sequenced individuals, it is critical to detect and remove those variants with poor quality as they may cause spurious findings. In...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Algorithms
• Share to Computational Biology