Article
An epistasis between dopaminergic and oxytocinergic systems confers risk of post-traumatic stress disorder in a traumatized Chinese cohort.
Scientific reports - 17 Dec 2019
Zhang Kunlin, Li Gen, Wang Li, Cao Chengqi, Fang Ruojiao, Luo Shu, Liu Ping, Zhang Xiang Yang
Abstract excerpt
Post-traumatic stress disorder (PTSD) is a psychiatric syndrome that occurs after trauma exposure. Neurotransmitters such as dopamine and oxytocin have been reported to be involved in neuropathology of PTSD. Previous studies indicated that the dopamine-oxytocin interaction may contribute to behavioral disorders. Thus, exploring the epistasis (gene-gene interaction) between oxytocinergic and dopaminergic systems...
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