Article
Genetic polymorphism patterns suggest a genetic driven inflammatory response as pathogenesis in appendicitis.
International journal of colorectal disease - 1 Feb 2020
Dimberg Jan, Rubér Marie, Skarstedt Marita, Andersson Manne, Andersson Roland E
Abstract excerpt
PURPOSE: The pathogenesis of appendicitis is not well understood. Environmental factors are regarded most important, but epidemiologic findings suggest a role of inflammatory and genetic mechanisms. This study determines the association of single nucleotide polymorphisms (SNPs) of inflammatory genes with appendicitis. METHODS: As part of a larger prospective study on the diagnostic value of inflammatory variables...
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