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A novel NR3C2 polymorphism and the increased thyroid-stimulating hormone concentration are associated with venlafaxine treatment outcome in Chinese Han MDD patients.

Psychiatry research - 1 Feb 2020

Yuan Fan, Yuan Ruixue, Ren Decheng, Bi Yan, Niu Weibo, Guo Zhenming, Wu Xi, Xu Fei, Sun Qianqian, Ma Gaini, Yang Fengping, Zhu Yuhao, Yu Tao, Li Xingwang, He Lin, Shi Lei, He Guang

Abstract excerpt

OBJECTIVE: We aimed to study the association among venlafaxine antidepressive outcome, NR3C2 gene polymorphisms and the change of two neuroendocrine hormones during treatment. METHODS: 195 Chinese Han major depressive disorder (MDD) patients were recruited and received a 6-week venlafaxine treatment in this study. Adrenocorticotropic hormone (ACTH), thyroid-stimulating hormone (TSH) levels were measured at the...

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PMID: 31757642
DOI: 10.1016/j.psychres.2019.112690

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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