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Article

Ion Binding and Selectivity of the Na+/H+ Antiporter MjNhaP1 from Experiment and Simulation.

The journal of physical chemistry. B - 16 Jan 2020

Warnau Judith, Wöhlert David, Okazaki Kei-Ichi, Yildiz Özkan, Gamiz-Hernandez Ana P, Kaila Ville R I, Kühlbrandt Werner, Hummer Gerhard

Abstract excerpt

Cells employ membrane-embedded antiporter proteins to control their pH, salt concentration, and volume. The large family of cation/proton antiporters is dominated by Na+/H+ antiporters that exchange sodium ions against protons, but homologous K+/H+ exchangers have recently been characterized. We show experimentally that the electroneutral antiporter NhaP1 of Methanocaldococcus jannaschii (MjNhaP1) is highly...

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Identifiers

PMID: 31841344
DOI: 10.1021/acs.jpcb.9b08552
PMCID: PMC6970264

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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