Article
Molecular phenotyping and image-guided surgical treatment of melanoma using spectrally distinct ultrasmall core-shell silica nanoparticles.
Science advances - 1 Dec 2019
Chen Feng, Madajewski Brian, Ma Kai, Karassawa Zanoni Daniella, Stambuk Hilda, Turker Melik Z, Monette Sébastien, Zhang Li, Yoo Barney, Chen Peiming, Meester Richard J C, de Jonge Sander, Montero Pablo, Phillips Evan, Quinn Thomas P, Gönen Mithat, Sequeira Sonia, de Stanchina Elisa, Zanzonico Pat, Wiesner Ulrich, Patel Snehal G, Bradbury Michelle S
Abstract excerpt
Accurate detection and quantification of metastases in regional lymph nodes remain a vital prognostic predictor for cancer staging and clinical outcomes. As intratumoral heterogeneity poses a major hurdle to effective treatment planning, more reliable image-guided, cancer-targeted optical multiplexing tools are critically needed in the operative suite. For sentinel lymph node mapping indications, accurately...
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