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Article

A Notch4 missense mutation is associated with susceptibility to tuberculosis in Chinese population.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Mar 2020

Zhang Jingwei, Jiao Lin, Bai Hao, Wu Qian, Wu Tao, Liu Tangyuheng, Hu Xuejiao, Song Jiajia, Ying Binwu

Abstract excerpt

BACKGROUND: The infection process of tuberculosis is related to the interactions between Mycobacterium tuberculosis (MTB) and the host immune system. Polymorphisms in genes involved in the host immune system are related to susceptibility to tuberculosis. The Notch signalling pathway regulates innate and adaptive immunity. Notch4 is a member of the Notch receptor family and may be a negative regulator of...

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Identifiers

PMID: 31838262
DOI: 10.1016/j.meegid.2019.104145

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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