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Article

Mouse genetics identifies unique and overlapping functions of fibroblast growth factor receptors in keratinocytes.

Journal of cellular and molecular medicine - 1 Jan 2020

Meyer Michael, Ben-Yehuda Greenwald Maya, Rauschendorfer Theresa, Sänger Catharina, Jukic Marko, Iizuka Haruka, Kubo Fumimasa, Chen Lin, Ornitz David M, Werner Sabine

Abstract excerpt

Fibroblast growth factors (FGFs) are key regulators of tissue development, homeostasis and repair, and abnormal FGF signalling is associated with various human diseases. In human and murine epidermis, FGF receptor 3 (FGFR3) activation causes benign skin tumours, but the consequences of FGFR3 deficiency in this tissue have not been determined. Here, we show that FGFR3 in keratinocytes is dispensable for mouse skin...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 31830366
DOI: 10.1111/jcmm.14871
PMCID: PMC6991627

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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